DelveInsight’s, “Malignant Pleural Effusion Pipeline Insight 2025” report provides comprehensive insights about 8+ companies and 8+ pipeline drugs in Malignant Pleural Effusion pipeline landscape. It covers the pipeline drug profiles, including clinical and nonclinical stage products. It also covers the therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.
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Key Takeaways from the Malignant Pleural Effusion Pipeline Report
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Malignant Pleural Effusion Emerging Drugs Profile
LIPAC is developing a new Liposomal Enhanced IntraThoracic Paclitaxel (LEITP) for the treatment of MPM utilizing the LiPax technology. Currently, the drug is being developed in the Pre-Clinical stage of clinical trial evaluation for the treatment of Malignant Pleural Effusion.
RSO-021 is a novel irreversible inhibitor of a key mitochondrial enzyme PRX3 (upregulated in cancer cells) regulating oxidative stress pathways. Treatment with RSO-021 will be administered weekly via an intrapleural catheter after routine pleural effusion drainage. RSO-021 therapy has proven to significantly reduce pre-clinically tumor burden in malignant mesothelioma and other cancer types by inhibiting three key enzymes in the antioxidant signaling network within the mitochondria. Covalent adduction of the active site of a key mitochondrial enzyme by RSO-021 inactivates the peroxidase activity of the enzymes leading to accumulation of hydrogen peroxide to levels incompatible with tumor cell survival, while preserving healthy normal cells. RSO-021 is being developed for the treatment of malignant pleural effusion (MPE) via intrapleural (IP) installation in patients suffering from mesothelioma, breast cancer and other indications causing MPE.
SCB-313, has been designed and developed utilizing the Trimer-Tag™ technology platform. SCB-313 is a covalently-linked, native-like trimeric fusion protein which is structurally and functionally differentiated from the dimeric antibody-based structures and other native ligand-based candidates targeting this pathway. SCB-313 has the potential to address the unmet global need for the treatment of intracavitary malignancies, including Malignant Ascites (MA), Malignant Pleural effusions (MPE), and Peritoneal carcinomatosis (PC), as well as additional cancer indications.
The Malignant Pleural Effusion Pipeline report provides insights into
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Malignant Pleural Effusion Companies
LIPAC Oncology, RS Oncology, Clover Biopharmaceuticals, Gongwin Biopharm Holdings, Simcere Pharmaceutical Group and others.
Malignant Pleural Effusion pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs such as
Malignant Pleural Effusion Products have been categorized under various Molecule types such as
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Scope of the Malignant Pleural Effusion Pipeline Report
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